Firstline - Clinical Decisions

Note

Lower drug levels achieved with oral dosage form of same drug.

Patient must be clinically improving prior to step-down.

Valacyclovir - dose based on indication

Amoxicillin 250 to 500 mg PO TID (1 g PO TID severe)

Clarithromycin XL 500 to 1000 mg PO daily

Azithromycin 250 to 500 mg PO daily

Cephalexin 250 to 500 mg PO QID (1 g PO QID severe)

Cefuroxime axetil 250 to 500 mg PO BID (TID severe)

Penicillin VK 300 to 600 mg PO QID (mild infections only)