IV to PO Conversion

Key Messages

Intravenous (IV) to oral (PO) administration of antimicrobials help increase patient mobility and reduces the chance of secondary IV line complications such as thrombophlebitis.

With appropriate IV to PO conversion, there is no difference in treatment success or mortality.

Assess for PO conversion using established criteria.

Clinical pharmacists will review and change route of antimicrobial administration using established criteria.

Oral Conversion Should Be Considered If Patient:

  • Continues to require antimicrobials AND

  • Is clinically stable AND

  • Is able to tolerate oral medications AND

  • Has no factors affecting oral absorption (e.g., presence of gastrointestinal abnormalities or drug interactions)

IV to Oral Stepdown

More Information

Guideline adapted from Providence Health Care, Vancouver

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