Ceftriaxone 2 g IV q12h
OR
Cefotaxime 2 g IV q4-6h
PLUS
Metronidazole 7.5 mg/kg IV q6h (or 15 mg/kg IV q12h)
Penicillin G 3-4 mu IV q4h
S. aureus
Streptococci
Bacteroides spp.
Enterobacteriaceae
Nocardia spp. (rare)
Listeria spp.
S. anginosus group
