Consider adding antifungal agent with activity against Candida
The regimen should also effectively treat C. difficile if it has not been excluded as a possible cause
Piperacillin/Tazobactam 3.375 g IV q6h (or 4.5 g IV q8h)
OR
Cefepime 2 g IV q8-12h
PLUS
Metronidazole 500 mg IV/PO q6-8h
Meropenem 1 g IV q8h
Imipenem 500 mg IV q6h (단독 없음; cilastatin과의 복합 주사제만 있음)
P. aeruginosa
B. fragilis
C. difficile
Enterobacteriaceae
Viridans streptococci
Enterococci
Candida spp.