Salmonella typhi

Precautions

Contact Precautions

General Information

Aerobic, gram-negative rod.

Humans are the reservoir - fecal-oral transmission.

Increased prevalence in developing countries.

Highest prevalence in South Asia.

  • Fever in Returning Traveler

  • Enteric fever

  • FUO (Fever of Unknown Origin)

  • Bacteremia

  • Intra-abdominal abscess

  • Meningitis

  • Endovascular infection including endocarditis and infected atherosclerotic plaque/aneurysm - "sticky" organism

Very high rates of FQ resistance in the Indian subcontinent.

Vaccination only prevents ~75% of disease.

Chronic carriage associated with gallbladder disease.

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