Aerobic, gram-negative rod.
Humans are the reservoir - fecal-oral transmission.
Increased prevalence in developing countries.
Highest prevalence in South Asia.
Fever in Returning Traveler
FUO (Fever of Unknown Origin)
Endovascular infection including endocarditis and infected atherosclerotic plaque/aneurysm - "sticky" organism
Very high rates of FQ resistance in the Indian subcontinent.
Vaccination only prevents ~75% of disease.
Chronic carriage associated with gallbladder disease.