ESBL Organisms

General Susceptibility

Considered resistant to all beta-lactams except for carbapenems, which are the preferred therapy.

These organisms may be reported as susceptible to Piperacillin/tazobactam or other beta-lactamase inhibitor combinations, however, treatment failures have been described.

Often resistant to fluoroquinolones, TMP/SMX, and aminoglycosides via other mechanisms.

For UTI only - may be susceptible to nitrofurantoin and fosfomycin.

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