General Spectrum of Activity
Monitor QTc in patients with increased risk.
Monitor fever, CBC, symptomatic improvement, hepatic and renal functions.
Recommend review of patient medications due to high frequency of significant interactions
Antimicrobial class: Macrolide
Pregnancy category: C
Average serum half life: 5 hours
Biliary penetration: Therapeutic
CSF penetration: Poor
Lung penetration: Therapeutic
Urine penetration: Poor
Very high tissue penetration and concentration intracellularly means in vivo activity may not be predicted by in vitro testing.