Skin and soft tissue infection (e.g. cellulitis).
Surgical prophylaxis.
Susceptible Staphylococcal, Streptococcal and gram-negative infections.
Monitor renal function, coagulation and prothrombin time.
Common
Serious
Seizure
Renal failure
Probenecid - prolonged half-life. Drug interaction has been used therapeutically to give once daily cefazolin.
Not recommended unless no other alternatives.
Antimicrobial class: 1st Generation Cephalosporin
Pregnancy category: B
Average serum half life: 2 hours
Biliary penetration: Therapeutic
CSF penetration: Poor
Lung penetration: Therapeutic
Urine penetration: Therapeutic
Precautions: