항생제
Ampicillin

Ampicillin

Low
N/A

General Information

Pathogen directed therapy for CNS, intravascular, intraabdominal, urinary and other infections especially Enterococcus and Listeria.

Monitor CBC, hematopoietic, hepatic and renal function.

When treating chronic urinary tract and intestinal infections, perform serological tests and monitor clinical response.

Perform serological tests in all cases where concomitant syphilis is suspected.

Common

  • Rash
  • Urticaria
  • Diarrhea

Serious

  • Erythema multiforme
  • Stevens-Johnson syndrome
  • Toxic epidermal necrolysis
  • Clostridium difficile colitis
  • Agranulocytosis
  • Thrombocytopenia
  • Anaphylaxis
  • Hypersensitivity reaction
  • Allopurinol- increased rash
  • Warfarin- increased risk of bleeding
  • Tetracyclines
  • Seizure threshold lowering agents
  • Cholera vaccine, live
  • Oral contraceptives

Antimicrobial class: Aminopenicillin

Pregnancy category: B

Average serum half life: 1 hour

Biliary penetration: Therapeutic

CSF penetration: Therapeutic

Lung penetration: Therapeutic

Urine penetration: Therapeutic

Precautions: Give cautiously to patients with history of hypersensitivity to multiple allergens due to increased risk of serious and potentially fatal hypersensitivity reaction.