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항생제
Amoxicillin

Amoxicillin

Low
Excellent

Spectrum Of Activity

General Spectrum of Activity
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General Information

Therapy of Streptococcal and Enterococcal infections as well as susceptible gram-negative infections.

Commonly used for upper respiratory infections and urinary tract infections.

Monitor CBC, renal function.

Perform culture and susceptibility tests during treatment, and clinical/bacteriological follow-up after discontinuation.

Common

  • Rash
  • Diarrhea
  • Nausea
  • Vomiting
  • Headache
  • Vulvovaginitis, mycotic

Serious

  • Stevens-Johnson syndrome
  • Toxic epidermal necrolysis
  • Erythema multiforme
  • Clostridium difficile diarrhea
  • Anaphylaxis
  • Hypersensitivity reaction
  • Allopurinol - increased rash
  • Mycophenolate mofetil
  • Tetracyclines
  • Methotrexate
  • Sulfasalazine
  • Venlafaxine
  • Cholera vaccine, live
  • Combination oral contraceptives

Antimicrobial class: Aminopenicillin

Pregnancy category: B

Average serum half life: 1 hour

Biliary penetration: Therapeutic

CSF penetration: Moderate

Lung penetration: Therapeutic

Urine penetration: Therapeutic

Precautions:

  • Discontinue if allergic reaction occurs.
  • Dose adjustment recommended with oral capsules, tablets, suspension, and chewable tablets in patients with severe renal impairment or hemodialysis.
  • Discontinuation may be required in Clostridium difficile-associated diarrhea or if anaphylactic reactions occur.