항생제
Aztreonam

Aztreonam

Medium
N/A

General Information

Therapy of gram-negative infections including Pseudomonas, particularly in patients with penicillin and cephalosporin allergy or when there is no alternative susceptible agent.

Nebulized form used in cystic fibrosis patients.

Empiric therapy for febrile neutropenia.

Monitor liver enzymes, renal and hepatic functions.

Common

  • Chest discomfort
  • Abdominal pain
  • Vomiting
  • Elevated liver enzymes
  • Serum creatinine raised
  • Cough
  • Nasal congestion
  • Throat pain
  • Wheezing
  • Fever

Serious

  • Erythema multiforme
  • Toxic epidermal necrolysis
  • Clostridium difficile colitis, diarrhea
  • Gastrointestinal hemorrhage
  • Neutropenia
  • Pancytopenia
  • Thrombocytopenia
  • Hepatitis
  • Jaundice
  • Ototoxicity
  • Nephrotoxicity
  • Angioedema
  • Anaphylaxis

Cholera vaccine, live

Antimicrobial class: Monobactam

Pregnancy category: B

Average serum half life: 2 hours

Biliary penetration: Moderate

Lung penetration: Therapeutic

Urine penetration: Therapeutic

Precautions:

  • Discontinue if allergic reaction or chest tightness occurs.
  • Pulmonary exacerbation may occur with reduction in FEV1 following completion of 28-day course.