제한된
Reserved for highly resistant infections or when significant allergies restrict other options and when there is documented susceptibility.
Black Box Warning: Associated with more treatment failures than alternatives and excess mortality. Tigecycline should be reserved for use in situations when alternative treatments are not suitable.
Perform bacteriological examination and sensitivity testing during initiation and for suspected relapse.
Monitor hepatic function for patients with abnormal liver function test, and severe hepatic impairment.
Obtain baseline blood coagulation panel, including fibrinogen, and monitor regularly during treatment.
Common
Serious
Contraindications:
Precautions:
Antimicrobial class: Tetracycline derivative, Glycylcycline
Pregnancy category: D
Average serum half life: 42 hours
Biliary penetration: Therapeutic
Lung penetration: Therapeutic
Requires Infectious Disease consultation.
Documented safety concerns in bacteremia especially.
항생제
