General Spectrum of Activity
Monitor QTc in patients with increased risk.
Multiple drug-drug interactions
Antimicrobial class: Macrolide
Pregnancy category: B
Average serum half life: 68 hours
Biliary penetration: Therapeutic
CSF penetration: Poor
Lung penetration: Therapeutic
Urine penetration: Poor
Very high tissue penetration and concentration intracellularly means in vivo activity may not be predicted by in vitro testing (e.g. Salmonella species).