항생제
Nitrofurantoin

Nitrofurantoin

Low
Excellent

Spectrum Of Activity

General Information

  • Urinary tract infectious disease.
  • Urinary tract infectious disease; prophylaxis.

Perform urine culture and sensitivity, before and after therapy.

Pulmonary function tests and X-ray (pulmonary infiltration with consolidation of pleural effusion).

Monitor EKG changes; hemolytic anemia; hepatic and renal functions; peripheral neuropathy; pulmonary hypersensitivity reaction.

Common

  • Loss of appetite
  • Nausea
  • Vomiting

Serious

  • Hemolytic anemia
  • Cholestatic jaundice syndrome
  • Hepatic necrosis
  • Hepatitis
  • Hypersensitivity reaction
  • Peripheral neuropathy
  • Pseudotumor cerebri
  • Interstitial pneumonia
  • Pulmonary fibrosis
  • Pulmonary hypersensitivity
  • Fluconazole - increased risk of hepatic and pulmonary toxicity
  • Cholera vaccine, live

Antimicrobial class: Nitrofuran

Pregnancy category: B

Average serum half life: 1 hour

Urine penetration: Therapeutic

This is not used to treat infections outside of the urinary tract.