Pseudomonal and other gram-negative infections of urinary tract, bone/joint, abdomen and other sites.
Black Box Warning: Fluoroquinolones, including ciprofloxacin, are associated with disabling and potentially irreversible serious adverse reactions, including tendinitis and tendon rupture, peripheral neuropathy, and CNS effects; discontinue and avoid use if adverse reactions occur. Avoid use in patients with known history of myasthenia gravis.
Monitor QTc in patients with increased risk.
Perform culture and susceptibility tests prior to and during therapy.
Monitor renal funcion and signs of hypersensitivity.
Antimicrobial class: Fluoroquinolone
Pregnancy category: C
Average serum half life: 4 hours
Biliary penetration: Therapeutic
CSF penetration: Moderate
Lung penetration: Therapeutic
Urine penetration: Therapeutic