General Spectrum of Activity
Follow creatinine and electrolytes in patients at increased risk renal failure, hyperkalemia.
Perform appropriate culture and susceptibility tests before treatment.
Perform microscopic urinalysis and renal function tests during therapy, particularly in patients with renal impairment.
Monitor for acid-base disturbances and CBC.
Multiple drug-drug interactions
Antimicrobial class: Sulfonamide - Antifolate
Pregnancy category: C
Average serum half life: 10 hours
Biliary penetration: Moderate
CSF penetration: Therapeutic
Lung penetration: Therapeutic
Urine penetration: Therapeutic