Cutaneous abscess, furuncle, carbuncle, inflamed epidermoid cyst
Ertapenem

Ertapenem

Medium
N/A

General Information

Targeted therapy of ESBL infections and other resistant gram-negative infections.

Empiric therapy when broad spectrum of carbapenems is desired without the need for anti-pseudomonal activity.

Monitor hematopoietic, renal, and hepatic function; periodically for patients with prolonged therapy.

Common

  • Abdominal pain
  • Constipation
  • Diarrhea
  • Nausea
  • Vomiting
  • Headache
  • Vaginitis
  • Neutrophil count abnormal

Serious

  • Seizure
  • Valproic acid - may decrease valproate levels and may decrease seizure threshold
  • Cholera vaccine, live
  • Tacrolimus
  • Probenecid

Antimicrobial class: Carbapenem

Pregnancy category: B

Average serum half life: 4 hours

Biliary penetration: Moderate

Lung penetration: Therapeutic

Urine penetration: Therapeutic

Precautions:

  • Use caution in patients with history of hypersensitivity to beta-lactam antibiotics and multiple allergens.
  • Not recommended in pediatric patients with meningitis due to lack of sufficient cerebrospinal fluid penetration.
  • Reduce dose or discontinue in patients with seizures or CNS adverse effects.