Peramivir

Dosing

Influenza treatment 600 mg IV (1 dose)

Safety and efficacy in pediatric patients <18y have not been established

CrCl ≥50CrCl 30-49CrCl 10-29No dose adjustment200 mg IV (1 dose)100 mg IV (1 dose)

General Information

Influenza, acute, uncomplicated

Monitor for signs of abnormal behavior.

Common

  • Diarrhea

Serious

  • Stevens-Johnson syndrome

  • Anaphylaxis

  • Abnormal behavior

  • Hallucinations

Influenza virus vaccine, live

Antimicrobial class: Antiviral, Neuraminidase inhibitor

Pregnancy category: C

Average serum half life: 20 hours

Precautions:

  • Dose adjustment recommended based on degree of renal impairment.

  • Discontinue if serious skin reactions occur or suspected.

  • Neuropsychiatric events have been reported; monitoring recommended.

  • Use not recommended in patients with serious influenza requiring hospitalization.

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