30 mg PO once daily

Safety and efficacy in pediatric patients <18y of age have not been established

No dose adjustment

CrCl <60 Avoid

General Information

Type B viral hepatitis, chronic.

Monitor HBV DNA.

Monitor ALT, HBeAg serum loss or seroconversion.

Perform liver function test.

  • Upper respiratory tract infection

  • Rash

  • Drowsiness

  • Headache

Drugs that reduce renal function or compete for active tubular secretion

Antimicrobial class: Antiviral agent, Pyrimidine nucleoside analog

Pregnancy category: Not recommended for use in pregnancy

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