General Spectrum of Activity
Type B viral hepatitis, chronic
Monitor liver and renal function.
Monitor serum L-carnitine levels.
Test for HIV antibodies prior to treatment.
Drugs that reduce renal function or compete for active tubular secretion
Antimicrobial class: Antiviral agent
Average serum half life:
2-3 hours (Besifovir), 45-90 hours (LB80317)
Severe acute exacerbations of HBV have been reported in patients who discontinued anti-hepatitis B therapy; monitoring recommended with clinical and laboratory follow-up.