Off-label
Strongyloidiasis: Obtain 1 stool culture per month for 3 months following treatment.
Onchocerciasis: Perform ophthalmic exam at baseline and periodically during treatment. Assess for loiasis prior to treatment with history of significant exposure to Loa loa-endemic areas.
Common
Serious
Warfarin- may elevate INR values
Antimicrobial class: Anthelmintic agent, Avermectin
Pregnancy category: C
Average serum half life: 18 hours (oral), 6.5 days (topical)
Precautions: Patients with onchocerciasis may have cutaenous, allergic and inflmmatory systemic, and ophthalmological reactions during oral use.
In patients with exposure to Loa loa endemic areas, pretreatment assessment for loiasis and careful monitoring is recommended.