Perform liver function test and SGOT prior to treatment and every 2-4 weeks after initiation.

Obtain CBC and blood uric acid levels prior to and during treatment.

• Fatigue
• Somnolence
• Headache
• Confusion
• Dizziness
• Loss of appetite
• Nausea
• Abdominal pain
• Flatulence
• Itching
• Urticaria
• Conjunctival hyperemia
• Peripheral neuritis
• Hyperuricemia
• Abnormal liver function
• Increased liver enzymes
• Liver toxicity
• Liver dysfunction
• Hepatitis
• Hypersensitivity reaction
• Anaphylaxis
• Tooth discoloration

Multiple drug-drug interactions

• Anticonvulsants
• Antiarrhythmic drugs
• Anticoagulants
• Antifungal drugs
• Barbituates
• Beta-blockers
• Calcium-channel antagonists