Spectrum Of Activity
Urinary tract infectious disease
Monitor serum drug levels periodically to maintain blood levels <30 mcg/mL.
Monitor renal and liver functions periodically.
Obtain hematologic panels periodically.
Monitor closely for CNS toxicity in patients receiving total dialy dose >500 mg.
Assess neruospychiatric statust at least monthly.
Ethionamide- increased risk of seizures
Antimicrobial class: Antitubercular, d-alanine analog
Pregnancy category: C
Average serum half life: 10-25 hours
CNS toxicity may occur; discontinue if condition develops.
Discontinue if allergic dermatitis develops.
Chronic alcoholics have an increased risk for convulsions.
Contraindicated in patients with epilepsy, depression, severe anxiety, psychosis, severe renal insufficiency, and excessive use of alcohol.