항생제
Terbinafine

Terbinafine

Spectrum Of Activity

General Information

  • Dermal mycosis
  • Onychomycosis due to dermatophyte
  • Tinea capitis

Perform negative potassium hydroxide (KOH) test and negative culture.

Monitor CBC including differential.

Perform liver function tests at baseline and periodically during therapy.

Common

  • Rash
  • Diarrhea
  • Disorder of taste
  • Indigestion
  • Nausea
  • Vomiting
  • Increased liver enzymes
  • Headache
  • Cough
  • Nasopharyngitis
  • Upper respiratory infection
  • Fever

Serious

  • Cutaneous lupus erythematosus
  • Erythema multiforme
  • Generalized exanthematous pustulosis (acute)
  • Stevens-Johnson syndrome
  • Toxic epidermal necrolysis
  • Neutropenic disorder (severe)
  • Thrombotic microangiopathy
  • Liver failure
  • Systemic lupus erythematosus
  • Hearing loss

CYP2D6 inhibitors

Antimicrobial class: Allylamine, Antifungal

Pregnancy category: B

Average serum half life: 36 hours

Precautions: Incidence of liver failure may be increased in patients with serious underlying systemic conditions and severity of hepatic adverse events may be increased with active or chronic liver disease; discontinue if suspected.

Discontinue if taste or smell disturbances are suspected.

Discontinue if serious skin reactions are suspected.