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항생제
Rifaximin

Rifaximin

Spectrum Of Activity

General Spectrum of Activity
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General Information

  • Hepatic encephalopathy; Prophylaxis.
  • Irritable bowel syndrome (with diarrhea).
  • Traveler's diarrhea, Noninvasive strains of E. coli.

Evaluate for Clostridium-associated diarrhea if diarrhea occurs after treatment or does not improve during treatment.

Common

  • Peripheral edema
  • Abdominal pain
  • Nausea
  • Dizziness
  • Ascites
  • Fatigue
  • Headache

Serious

  • Anemia
  • Hypersensitivity reaction
  • Cholera vaccine, live
  • Lixisenatide
  • Warfarin- potential effect on INR

Antimicrobial class: Rifamycin

Pregnancy category: C

Average serum half life: 2-5 hours

CSF penetration: Poor

Precautions: Use with caution in patients with severe (Child-Pugh Class C) hepatic impairment due to increased systemic exposure.

Rifaximin was not effective in diarrhea complicated by fever and/or blood in the stool or diarrhea due to pathogens other than E. coli. If diarrhea symptoms get worse or persist for more than 24-48 hours, discontinue and consider alternative antibiotics.