Cefoperazone/Sulbactam

Dosing

Usual dose 1-2 g IV q12h (Cefoperazone component)

No data

Severe hepatic dysfunction or with concomitant hepatic and renal dysfunction May require dose adjustment

CrCl 15-30CrCl <151 g IV q12h500 mg IV q12h

General Information

Treat variety of respiratory, skin-soft tissue, urinary tract and intra-abdominal infections.

  • Increase PT/INR

Administration of ethanol may lead to reaction with:

  • Flushing

  • Sweating

  • Headache

  • Tachycardia

Diuretics (i.e. Furosemide)

Antimicrobial class: 3rd Generation Cephalosporin

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