General Spectrum of Activity
Monitor fever; CBC; symptomatic improvement; hepatic and renal functions.
Monitor previous hypersensitivity to other beta-lactam antibiotics.
Monitor signs of serum-sickness-like reactions, and antibiotic-associated diarrhea.
Antimicrobial class: 3rd Generation Cephalosporin
Pregnancy category: B
Average serum half life: 1.7 hour
Biliary penetration: Therapeutic
CSF penetration: Therapeutic
Lung penetration: Therapeutic
Urine penetration: Therapeutic
Dose reduction recommended in patients with renal insufficiency.
Emergence and overgrowth of resistant pathogens may occur with prolonged therapy; close observation recommended; alternative therapy is required if superinfection occurs.
Use with caution in patients with history of colitis and penicillin hypersensitivity.
Oral suspension contains sucrose and should be used with caution in patients with diabetes.