Cefbuperazone

제한된
0
C. difficile 위험도
Low
경구생체이용률
N/A

Dosing

1-2 g IV #2 (max 4 g/d , if severe)No renal dose adjustment

Safety and efficacy in neonates and infants have not been established*

40-80 mg/kg IV #2-4 (max 120 mg/kg, if severe)No renal dose adjustment

No dose adjustment

General Information

  • Sepsis

  • Infective endocarditis

  • Chronic bronchitis

  • Bronchiectasis

  • Pneumonia

  • Pulmonary abscess

  • Empyema

  • Pyelonephritis

  • Cystitis

  • Cholecystitis

  • Cholangitis

  • Adnexitis

  • Intrauterine infection

  • Bartholinits

Monitor infusion rate to prevent thrombophlebitis.

Monitor status of elderly patients due to risk of hemorrhage.

Perform skin reaction test prior to treatment.

Monitor renal function, especially in severe patients receiving maximum dose.

  • Rash

  • Hives

  • Erythema

  • Itchiness

  • Fever

  • Nausea

  • Vomiting

  • Loss of appetite

  • Diarrhea

  • Abdominal pain

  • Seizure

  • Hypoprothrombinemia

  • Abnormal liver function

  • Hypersensitivity reaction

  • Anaphylaxis (rare)

  • Furosemide- may increase nephrotoxicity

  • Aminoglycoside

  • Cephalosporin

  • Probenecid

Antimicrobial class: Cephamycin

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