Spectrum Of Activity
Mild to moderate infection 250 mg PO q8h
Severe infection (pneumonia) 500 mg PO q8h
(max 6 g/d, if severe)No renal dose adjustment
Safety and efficacy in pediatric patients <1m of age have not been established
Mild to moderate infection 20 mg/kg PO #3
Severe infection (otitis media) 40 mg/kg PO #3 (max 1 g/d)No renal dose adjustment
No dose adjustment
Acute bacterial exacerbation of chronic bronchitis
Acute otitis media
Bronchitis, acute- Secondary bacterial infection
Infection of skin and/or subcutaneous tissue
Lower respiratory tract infection
Urinary tract infectious disease
Monitor fever, CBC, previous hypersensitivity to other beta-lactam antibiotics, hypersensitivity to other beta-lactam antibiotics, signs of antibiotic-associated diarrhea and serum-sickness-like reactions.
Monitor liver and renal functions.
Toxic epidermal necrolysis
Clostridium difficile colitis
Cholera vaccine, live
Combination oral contraceptives
Antimicrobial class: 2nd Generation Cephalosporin
Pregnancy category: B
Average serum half life: 0.8 hour
Precautions: Discontinuation may be required in Clostridium difficile-associated diarrhea.
Use caution in patients with history of gastrointestinal disease particularly colitis; hypersensitivity to penicillins; renal impairment.