Sofosbuvir
소아

소아

국내허가사항

만12세 미만의 소아에 대한 이 약의 안전성 및 유효성은 입증되지 않았으며 이용 가능한 데이터가 없다

  • Safety and efficacy in pediatric patients with Genotypes 1 or 4 HCV have not been established
  • Safety and efficacy in post-liver transplant patients have not established
  • Take with food

Genotype 2, 3

Age ≥3y
  • BW >80 kg: 400 mg PO once daily + Ribavirin 600 mg twice daily
  • BW 66-80 kg: 400 mg PO once daily + Ribavirin 400 mg PO qAM and 600 qPM
  • BW 50-65 kg: 400 mg PO once daily + Ribavirin 400 mg PO twice daily
  • BW 47-49 kg: 400 mg PO once daily + Ribavirin 200 mg PO qAM and 400 mg qPM
  • BW 35-46 kg: 400 mg PO once daily + Ribavirin 15 mg/kg/d PO (2 divided doses)
  • BW 17-34 kg: 200 mg PO once daily + Ribavirin 15 mg/kg/d PO (2 divided doses)
  • BW <17 kg: 150 mg PO once daily + Ribavirin 15 mg/kg/d PO (2 divided doses)
Age ≥3y: Without cirrhosis or with compensated cirrhosis in combination with Ribavirin
  • Genotype 2: x12w
  • Genotype 3: x24w
Age ≥3y: Liver carcinoma, Awaiting liver transplantation

Up to 48w or until transplantation

No renal dose adjustment