항생제
Raltegravir

Raltegravir

Spectrum Of Activity

General Information

Treatment for HIV infection and used as part of a 3-drug combination regimen.

Monitor viral load prior to initiation or modification of treatment.

Monitor CD4 cell counts prior to initiation or with modification of ARV treatment and every 3-6 months; thereafter during at least the first 2 years of treatment.

Monitor hepatitis B screening at baseline and with modification of ARV treatment.

Perform hepatitis C antibody testing prior to initiation or modification of ARV treatment.

Monitor ALT,AST, and total bilirubin.

Monitor fasting blood glucose or HbA1c at baseline and with modification of ARV treatment.

Common

  • Nausea
  • Headache
  • Insomnia
  • Fatigue

Serious

  • Stevens-Johnson syndrome
  • Toxic epidermal necrolysis
  • Hypersensitivity
  • Rhabdomyolysis
  • Suicidal
  • Renal failure
  • Al or Mg antacids
  • Fosampernavir
  • Carbotegravir
  • Orlistat
  • Medications containing polyvalent cations

Antimicrobial class: Antiretroviral agent, Integrase Inhibitor

Pregnancy category: C

Average serum half life: 9 hours

Precautions: Discontinue use immediately if signs or symptoms of skin reactions develop.

Immune reconstitution syndrome has been reported; monitoring recommended; further evaluation and treatment of opportunistic infections may be necessary.

Chewable tablets contain phenylalanine.