General Spectrum of Activity
Resolution in the signs and symptoms of acute, uncomplicated Plasmodium falciparum malaria is indicative of efficacy.
Monitor closely for parasitemia in patients who are vomiting.
Major drug-drug interactions:
Antimicrobial class: Quinone, Biguanide
Pregnancy category: C
Average serum half life: 2-3 days (adults), 1-2 days (pediatrics)