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항생제
Anidulafungin

Anidulafungin

제한된

N/A
N/A

Spectrum Of Activity

General Spectrum of Activity
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General Information

  • Candidemia
  • Candidiasis of the esophagus
  • Candidiasis of the esophagus - HIV infection
  • Invasive candidiasis, Intra-abdominal and peritonitis

Prior to initiation, obtain specimens for fungal culture and other relevant laboratory studies (including histopathology).

Improvement in signs and symptoms of fungal infection is indicative of efficacy.

Monitor hepatic function during therapy.

Common

  • Hypokalemia
  • Diarrhea

Serious

  • Deep venous thrombosis
  • Abnormal liver function
  • Hepatic necrosis
  • Anaphylaxis
  • Hypersensitivity reaction
  • Seizure

No significant interactions

Antimicrobial class: Antifungal, Echinocandins, Glucans Synthesis Inhibitor

Pregnancy category: B

Average serum half life: 26.5 hours

Urine penetration: Therapeutic

Precautions:

  • Monitoring recommended for liver function test abnormalities.
  • Discontinue use if anaphylactic reactions occur.
  • Risk of metabolic crisis in patients with hereditary fructose intolerance (HFI). Obtain history of HFI symptoms with exposure prior to treatment.