Spectrum Of Activity
Female genital infection
Infection of skin and/or subcutaneous tissue
Infectious disease of abdomen
Pelvic inflammatory disease
Urinary tract infectious disease
Respiratory tract infection
Monitor fever, symptomatic improvement, CBC, and hepatic and renal functions.
Check previous hypersensitivity to other beta-lactam antibiotics.
Monitor prothrombin time in patients at risk.
Monitor signs of antibiotic-associated diarrhea, serum-sickness-like reactions, and thrombophlebitis.
Injection site phlebitis/pain
Toxic epidermal necrolysis
Vitamin K deficiency
Warfarin, Heparin - increased risk of bleeding
Cholera vaccine, live
Typhoid vaccine, live
Antimicrobial class: 3rd Generation Cephalosporin
Pregnancy category: B
Average serum half life: 2 hours
Urine penetration: Therapeutic
Lung penetration Therapeutic
CSF penetration: Therapeutic
Biliary penetration: Therapeutic
Exercise with caution in patients with history of GI disease, especially colitis.
Monitor for vitamin K deficiency.
Hepatic impairment and comorbid significant renal disease requires monitoring if high dosages are used.
Use cautiously in beta-lactam allergy patients.
Discontinue if allergic reaction occurs.