Perform liver function tests (ALT and AST levels) at baseline.
Perform bilirubin level, serum creatinine level, and CBC panel (including platelets) at baseline and continue follow-up monitoring in patients who have abnormalities.
Obtain acid-fast bacilli smear and culture from sputum until 2 consecutive culture specimens are negative.
Perform chest x-rays after 2-3 months of treatment and at end of treatment.
Monitor coagulation tests in patients at risk of vitamin K deficiency.