Colistin
신기능 저하

신기능 저하

CrCl ≥80

No dose adjustment

CrCl 50-79

2.5-3.8 mg/kg IV #2

CrCl 30-49

2.5 mg/kg IV #1-2

CrCl <10

1.5 mg/kg IV q36h

Non-HD days

65 mg IV q12h (130 mg/d)

HD days

Daily dose + 40-50 mg after a 3-4h session (give this supplement with the next regular dose after the dialysis has ended)

CRRT

220 mg q12h (442 mg/d divided q12h)

65 mg + (13 mg per hour of CRRT) q12h = 221 mg q12h