Pregnancy: Moxifloxacin crosses the placenta. There is very limited data on moxifloxacin use during pregnancy. In general, fluoroquinolone use during pregnancy has not been associated with congenital malformations or evidence of cartilage damage or tendon rupture in newborns. Fluoroquinolones and their effect on joint development are still being studied.
Fluoroquinolones should only be used during pregnancy in the absence of other alternatives to treat the infection.
Breastfeeding: No data is available for moxifloxacin in breastfeeding. It may be preferable to use an alternative until safety information is available. If a fluoroquinolone is required, an alternative fluoroquinolone with more information may be preferable (see ciprofloxacin or levofloxacin depending on indication).