Linezolid is a weak, reversible, non-selective monoamine oxidase inhibitor (MAOI).
Multiple drug interactions are possible. Consult pharmacy.
SSRI and other serotonergics/MAOIs - increased risk of serotonin syndrome (this includes opioids)
Rifampin decreases linezolid levels
Use cautiously and monitor blood pressure when administering together with any sympathomimetic amine (dopamine, dobutamine, epinephrine, isoproterenol, norepinephrine, phenylephrine)