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Antimicrobiens
Ertapenem

Ertapenem

High
N/A

Spectrum of Activity

General Spectrum of Activity
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Dosing

General Information

Pregnancy:

  • No published human data.
  • No teratogenicity was observed in animal studies.
  • There is no evidence that any beta-lactam antibiotic causes developmental toxicity in humans at therapeutic doses, therefore, if ertapenem is required by the mother, benefit outweighs the unknown risks.

Breastfeeding:

  • Compatible.

Targeted therapy of ESBL infections and other resistant gram negative infections

Empiric therapy when broad spectrum of carbapenems is desired without the need for anti-pseudomonal activity

  • Immediate and delayed-type allergy
  • GI disturbance
  • Cytopenias, eosinophilia, positive Coombs
  • Liver enzyme abnormalities
  • Seizure risk lower than other carbapenems

Antimicrobial class: Carbapenem