If an alternate non-infectious diagnosis is more likely, immediately discontinue antimicrobials.
Target therapy based on bacterial identification and susceptibility results
Consider oral step-down for earlier hospital discharge.
The unnecessary use of broad spectrum antimicrobials is a significant contributor to antimicrobial resistance in Newfoundland and Labrador.
At day 3 of treatment, please narrow spectrum or discontinue antimicrobials if possible.
Consider shortening the duration of treatment.
Once the patient is improving clinically, additional treatment may be harmful to the patient's microbiome.