In the setting of rapidly improving/worsening renal function, calculations of eGFR are inaccurate, and dosing should be based on estimated renal function instead.
If worsening renal function, actual GFR is likely lower than calculated.
If improving renal function, actual GFR is likely higher than calculated eGFR.
Non Dialysé
Aucun ajustement de dose requis
1000 mg PO x 1 dose puis 500 mg PO q 12 heures
1000 mg PO x 1 dose puis 500 mg PO q 24 heures
Hémodialyse (HD)
500-1000mg PO 3x/semaine (les jours de dialyse)