In the setting of rapidly improving/worsening renal function, calculations of eGFR are inaccurate, and dosing should be based on estimated renal function instead.
If worsening renal function, actual GFR is likely lower than calculated.
If improving renal function, actual GFR is likely higher than calculated eGFR.
Non dialysés
PO infections sévères: 750 mg BID
IV: 400 mg BID
IV infections sévères: 400 mg TID
PO Infections sévères: 750 mg DIE
IV: 200 mg BID ou 400 mg DIE (peu importe la sévérité de l'infection)
Hémodialyse (HD)
PO Infections sévères: 750 mg DIE
IV: 200 à 400 mg DIE
Ciprofloxacine