Antimicrobials
Cefazolin

Cefazolin

Medium
N/A

Dosing

General Information

  • Skin and soft tissue infection (i.e. cellulitis)
  • Surgical prophylaxis
  • Susceptible Staphylococcal, Streptococcal and Gram negative infections
  • Allergy (immediate or delayed)
  • Can cause positive Coombs, cytopenias, and hepatic and renal laboratory abnormalities

Probenecid prolongs the half-life of cefazolin allowing it to be used for once daily therapy. This usage is limited to once daily outpatient parenteral antimicrobial therapy. Inpatient usage not recommended.

Antimicrobial class: 1st Generation Cephalosporin

Pregnancy category: B