Amikacin
Renal

Renal

Dosing Notes

Obese patients are dosed according to Dosing Body Weight (DBW). Consult pharmacist or refer to "Additional Information" section for details.

Round to nearest 50 mg

Not On Dialysis: Extended Interval Dosing (CrCl)

60+ mL/min

15 mg/kg IV q24h

40 - 59 mL/min

15 mg/kg IV q36h

0 - 40 mL/min

Refer to conventional dosing

Not On Dialysis: Conventional Dosing (CrCl)

50+ mL/min

7.5 mg/kg IV q12h

20 - 49 mL/min

7.5 mg/kg IV q24h and consult pharmacist

0 - 20 mL/min

7.5 mg/kg IV once and consult pharmacist

Not On Dialysis: Synergy dosing

Not recommended. Use gentamicin.

Intermittent Hemodialysis

7.5 mg/kg IV qHD Consult pharmacist

CVVHDF

10 mg/kg IV load, then 7.5 mg/kg IV q24-48h Consult pharmacist

PD

7.5 mg/kg IV once and consult pharmacist