Antimicrobials
Acyclovir

Acyclovir

None
N/A

Spectrum of Activity

Dosing

General Information

GI upset, phlebitis- common

Increased SCr, AKI from crystal nephropathy

Mycophenolate can increase the acyclovir concentration

May diminish efficacy of zoster or varicella vaccine

Consider providing hydration prior to giving dose to prevent nephrotoxicity

Antimicrobial class: Antiviral, nucleoside analogue

Pregnancy category: B