Antimicrobials
Levofloxacin

Levofloxacin

High
Excellent

Spectrum of Activity

Dosing

General Information

Monitor QTc in patients with increased risk

  • QTc prolongation
  • Dysglycemia
  • CNS toxicity including confusion, psychosis
  • Tendinopathy and rupture
  • GI upset
  • Weakness exacerbation in myasthenia gravis
  • Rash
  • Other QTc prolonging agents
  • Di- & Trivalent cations including Al, Ca, Fe, Mg (antacids, dairy products, iron supplements, some enteral feeds) - decreased absorption
  • NSAIDs - increase seizure risk
  • Warfarin - increased INR

May exacerbate muscle weakness in persons with myasthenia gravis. Avoid Use.

Antimicrobial class: Fluoroquinolone

Pregnancy category: C