Antimicrobials
Nitrofurantoin

Nitrofurantoin

C difficile risk
Low
Oral Bioavailability
Excellent

Spectrum Of Activity

Dosing

100 mg PO BID (MacroBID)

30+ mL/min0 - 29 mL/min100 mg PO BIDAVOID

General Information

DO NOT use for pyelonephritis or bacteremia as insufficient systemic drug levels.

Interstitial pneumonitis and fibrosis esp. with prolonged use

Peripheral neuropathy

Antacids decrease absorption

Pregnancy category: B

Urine penetration: Therapeutic

Lung penetration: None

CSF penetration: None

Biliary penetration: None