General treatment duration 10 days. May be longer in poor responders or patients on concomitant antibiotics.
Cholestyramine may bind other oral medication (ie PO vanco). Not recommended.
Metronidazole no longer recommended first line by IDSA guidelines.
In refractory cases, fecal microbiota transplants have been effective. Rebyota is an FDA-approved live biotherapeutic enema approved for recurrent CDI prevention.