Contact Precautions
Gram negative organisms with enzymes that confer resistance to 3rd generation cephalosporins in addition to lower order beta-lactams.
Community-acquired and nosocomial infections occur, especially if patient has received antimicrobials or has traveled to areas of high prevalence (i.e. Asia/India).
Human-to-human transmission occurs and outbreaks have been described.
Can also pick up from environment/water, surfaces, animals, and meat.
ESBLs vs. AmpC: Most ESBLs are plasmid-encoded, whereas AmpCs are usually inducible and chromosomal.
In the lab, ESBL testing is performed at BC and if positive a note ESBL producing organism comment will be listed.