Antimicrobials
Nafcillin

Nafcillin

Medium
N/A
$40-50/day

Spectrum of Activity

Dosing

General Information

Serious MSSA infections (CNS, Endocarditis)

CBC weekly - Monitor for neutropenia

Generally reserved for the more serious MSSA infections.

More side effects and more costly than cefazolin.

Antimicrobial class: antistaphylococcal penicillin

Pregnancy category: B

Average serum half life: 0.5 to 1 hour

CSF penetration: Drug of choice for MSSA brain abscess

Route of Elimination: hepatic

No renal adjustment required